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Shire Human Genetic Therapies Inc.

Exact employer profile · All loaded years

Matching filings265

Median yearly base wage$110,000n=213 eligible

Middle 50% of yearly wages$85,000 – $138,690

Most reported worksiteLexington, MA186 matching filings

Explore this companyMost reported roleDownstream Development Engineer Ii Top worksiteLexington Individual recordsInspect dates & base salaries

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Salary records

265 matching H-1B filings

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Reported base wages in USD · pay period shown beside each amount · select a salary for case details

Employer	Job title	Base salary	Location	Submit date	Start date
Shire Human Genetic Therapies Inc.	Senior Process Validation Engineer I	Filing details $113,074.9 /yr I-200-26167-021590 Reported wage: $113,074.9 / year Annualized: $113,075 Status: Certified Fiscal year: 2026 Decision: 2026-06-24 Employment end: 2029-11-29 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	06/16/2026	11/30/2026
Shire Human Genetic Therapies Inc.	Sr. Validation Engineer	Filing details $133,120 /yr I-200-26161-003179 Reported wage: $133,120 / year Annualized: $133,120 Status: Certified Fiscal year: 2026 Decision: 2026-06-17 Employment end: 2029-11-26 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	06/10/2026	11/27/2026
Shire Human Genetic Therapies Inc.	Project Management, Principal Analyst	Filing details $140,000 /yr I-200-26148-959786 Reported wage: $140,000 / year Annualized: $140,000 Status: Certified Fiscal year: 2026 Decision: 2026-06-04 Employment end: 2027-11-17 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	05/28/2026	11/18/2026
Shire Human Genetic Therapies Inc.	Senior Validation Engineer I	Filing details $112,000 /yr I-200-26147-954582 Reported wage: $112,000 / year Annualized: $112,000 Status: Certified Fiscal year: 2026 Decision: 2026-06-03 Employment end: 2029-11-12 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	05/27/2026	11/13/2026
Shire Human Genetic Therapies Inc.	Automation Hardware Engineer	Filing details $196,950 /yr I-200-26126-874442 Reported wage: $196,950 / year Annualized: $196,950 Status: Certified Fiscal year: 2026 Decision: 2026-05-13 Employment end: 2029-09-30 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	05/06/2026	10/01/2026
Shire Human Genetic Therapies Inc.	Validation Manager	Filing details $169,914.08 /yr I-200-25345-474475 Reported wage: $169,914.08 / year Annualized: $169,914 Status: Certified Fiscal year: 2026 Decision: 2025-12-18 Employment end: 2029-04-19 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	12/11/2025	04/20/2026
Shire Human Genetic Therapies Inc.	Scientist	Filing details $106,012 /yr I-200-24123-952053 Reported wage: $106,012 / year Annualized: $106,012 Status: Certified - Withdrawn Fiscal year: 2025 Decision: 2025-09-03 Employment end: 2027-09-30 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	05/02/2024	10/01/2024
Shire Human Genetic Therapies Inc.	Quality Manager - Qa Operations	Filing details $147,732.84 /yr I-200-25232-256705 Reported wage: $147,732.84 / year Annualized: $147,733 Status: Certified Fiscal year: 2025 Decision: 2025-08-27 Employment end: 2029-02-08 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	08/20/2025	02/09/2026
Shire Human Genetic Therapies Inc.	Automation Engineer	Filing details $93,000 /yr I-200-25217-223292 Reported wage: $93,000 / year Annualized: $93,000 Status: Certified Fiscal year: 2025 Decision: 2025-08-12 Employment end: 2028-10-12 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	08/05/2025	10/13/2025
Shire Human Genetic Therapies Inc.	Senior Process Validation Engineer I	Filing details $109,781.48 /yr I-200-25197-178709 Reported wage: $109,781.48 / year Annualized: $109,781 Status: Certified Fiscal year: 2025 Decision: 2025-07-23 Employment end: 2026-11-29 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	07/16/2025	11/30/2025
Shire Human Genetic Therapies Inc.	Director, Head Of Manufacturing Science Downstream	Filing details $225,000 /yr I-200-25104-861147 Reported wage: $225,000 / year Annualized: $225,000 Status: Certified Fiscal year: 2025 Decision: 2025-04-21 Employment end: 2028-04-22 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	04/14/2025	04/23/2025
Shire Human Genetic Therapies Inc.	Senior Manager, Process Engineering	Filing details $160,774.95 /yr I-200-25062-739454 Reported wage: $160,774.95 / year Annualized: $160,775 Status: Certified Fiscal year: 2025 Decision: 2025-03-10 Employment end: 2028-08-07 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	03/03/2025	08/08/2025
Shire Human Genetic Therapies, Inc.	Senior Validation Engineer	Filing details $128,426.48 /yr I-200-25013-613510 Reported wage: $128,426.48 / year Annualized: $128,426 Status: Certified Fiscal year: 2025 Decision: 2025-01-21 Employment end: 2028-06-03 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	01/13/2025	06/04/2025
Shire Human Genetic Therapies Inc.	Senior Development Engineer I - Downstream	Filing details $105,000 /yr I-200-22032-869850 Reported wage: $105,000 / year Annualized: $105,000 Status: Certified - Withdrawn Fiscal year: 2025 Decision: 2024-12-12 Employment end: 2025-07-30 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	02/01/2022	07/31/2022
Shire Human Genetic Therapies Inc.	Qc Analyst Ii	Filing details $85,000 /yr I-200-24241-299385 Reported wage: $85,000 / year Annualized: $85,000 Status: Certified Fiscal year: 2024 Decision: 2024-09-05 Employment end: 2027-10-13 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	08/28/2024	10/14/2024
Shire Human Genetic Therapies Inc.	Project Portfolio Specialist	Filing details $126,560.82 /yr I-200-24221-253734 Reported wage: $126,560.82 / year Annualized: $126,561 Status: Certified Fiscal year: 2024 Decision: 2024-08-15 Employment end: 2028-02-06 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	08/08/2024	02/07/2025
Shire Human Genetic Therapies Inc.	Validation Engineer - Process Validation, Professional Ii	Filing details $101,706.22 /yr I-200-24185-173618 Reported wage: $101,706.22 / year Annualized: $101,706 Status: Certified Fiscal year: 2024 Decision: 2024-07-11 Employment end: 2025-11-29 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	07/03/2024	12/01/2024
Shire Human Genetic Therapies Inc.	Senior Engineer Ii	Filing details $138,820 /yr I-200-24166-112481 Reported wage: $138,820 / year Annualized: $138,820 Status: Certified Fiscal year: 2024 Decision: 2024-06-24 Employment end: 2027-11-14 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	06/14/2024	11/15/2024
Shire Human Genetic Therapies Inc.	Cmc Submission Lead	Filing details $97,000 /yr I-200-24143-025204 Reported wage: $97,000 / year Annualized: $97,000 Status: Certified Fiscal year: 2024 Decision: 2024-05-30 Employment end: 2027-09-30 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	05/22/2024	10/01/2024
Shire Human Genetic Therapies Inc.	Team Lead, Device Regulatory Affairs, Pdt Bu	Filing details $210,250.52 /yr I-200-24082-825268 Reported wage: $210,250.52 / year Annualized: $210,251 Status: Certified Fiscal year: 2024 Decision: 2024-03-29 Employment end: 2027-03-31 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	03/22/2024	04/01/2024
Shire Human Genetic Therapies Inc.	Regulatory Lead	Filing details $152,193.46 /yr I-200-24068-782802 Reported wage: $152,193.46 / year Annualized: $152,193 Status: Certified Fiscal year: 2024 Decision: 2024-03-15 Employment end: 2027-03-14 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Cambridge, MA	03/08/2024	03/15/2024
Shire Human Genetic Therapies Inc.	Senior Validation Engineer Ii	Filing details $154,166 /yr I-200-24064-768247 Reported wage: $154,166 / year Annualized: $154,166 Status: Certified Fiscal year: 2024 Decision: 2024-03-11 Employment end: 2027-08-22 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	03/04/2024	08/23/2024
Shire Human Genetic Therapies Inc.	Regulatory Lead	Filing details $152,193.46 /yr I-200-24060-758571 Reported wage: $152,193.46 / year Annualized: $152,193 Status: Certified Fiscal year: 2024 Decision: 2024-03-07 Employment end: 2027-08-26 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Cambridge, MA	02/29/2024	08/27/2024
Shire Human Genetic Therapies Inc.	Director, Quality Risk Management	Filing details $197,450 /yr I-200-24038-701760 Reported wage: $197,450 / year Annualized: $197,450 Status: Certified Fiscal year: 2024 Decision: 2024-02-14 Employment end: 2027-06-04 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Lexington, MA	02/07/2024	06/05/2024
Shire Human Genetic Therapies Inc.	Engineer I	Filing details $75,000 /yr I-200-22132-165030 Reported wage: $75,000 / year Annualized: $75,000 Status: Certified - Withdrawn Fiscal year: 2024 Decision: 2024-02-13 Employment end: 2025-09-30 Worker positions: 1 Employer-reported disclosure · Base wage, not total compensation.	Cambridge, MA	05/12/2022	10/01/2022

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About Shire Human Genetic Therapies Inc. H-1B salary records

This view contains 265 matching filings across all loaded fiscal years. The median reported yearly base wage is $110,000, based on 213 certified filings with positive yearly pay. These are filing-level observations, not unique employees or total compensation.

Read each filing in context.

Base wages preserve the disclosed pay period. Select a salary to see its case status, dates, worker positions, and annualized estimate. Salary charts use certified, positive yearly base wages; LCAs are not visa approvals. Subsidiaries and previous legal names have separate profiles. Methodology & coverage ↗

THE BIG PICTURE

Shire Human Genetic Therapies Inc. insights

Official U.S. DOL records

Filing & salary trends

How reported activity and wages changed over time

All loaded years · FY 2016–2026

FY 2026*6 filings$136,560 median · n=6

*FY 2026 covers Q1–Q3 through June; earlier years cover full fiscal years. Median: certified, positive yearly base wages; nominal USD.

Salary distribution

Where reported yearly base wages concentrate

All loaded years · FY 2016–2026

$100k–$125kMost common wage band

$0$125k$250k+

$25k bands · 213 certified filings with positive yearly wages. Final band includes all wages ≥$250k.

Salary ranges by role

Which common roles report higher base wages?

All loaded years · FY 2016–2026

Not enough eligible records to compare groups. Each group needs at least 20.

Up to six of the eight most-filed roles, ordered by median pay. At least 20 certified, positive yearly wages per group. Bars compare median yearly base salary from a zero baseline. Typical range contains the middle 50% of wages. Click a group to inspect its filings.

Salary ranges by city

How does reported pay differ across common worksites?

All loaded years · FY 2016–2026

Cambridge, MA$125,000 median

Typical range: $101,300–$146,72136 salary records

LEXINGTON, MA$112,698 median

Typical range: $84,636–$139,036147 salary records

Lexington, MASSACHUSETTS$96,030 median

Typical range: $80,185–$110,00021 salary records

$0$75,000$150,000

Up to six of the eight most-filed worksites, ordered by median pay. At least 20 certified, positive yearly wages per group. Bars compare median yearly base salary from a zero baseline. Typical range contains the middle 50% of wages. Click a group to inspect its filings.

Case outcomes

Certification and withdrawal context

All loaded years · FY 2016–2026

80.4%Certified LCAs

Certified213 80.4%

Certified - Withdrawn39 14.7%

Withdrawn9 3.4%

Denied4 1.5%

Denominator: all 265 matching filings. LCA certification is not a visa approval rate.

Salary benchmarks

Reported wage percentiles, from P10 to P90

All loaded years · FY 2016–2026

$110,000Median reported annual base wage

10th percentile$71,791

25th percentile$85,000

Median (50th)$110,000

75th percentile$138,690

90th percentile$167,259

n=213 certified filings with positive yearly wages. Percentiles describe filings, not unique workers or total compensation.

Source: U.S. Department of Labor LCA disclosures · FY 2016–2026 (FY 2026 partial) · salary charts exclude non-yearly pay, non-certified cases, and missing or non-positive wages. Coverage & methodology