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Senior Principal Scientist

Reported H-1B wages for this job title. Explore roles, wages, and case statuses using public Department of Labor records.

Insights follow the displayed search filters, including partial name matches. All loaded years.

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THE BIG PICTURE

Senior Principal Scientist insights

Official U.S. DOL records
Total filings78All loaded years · FY 2016–2026
Median yearly base salary$150,70071 eligible salary records
Employer names39Distinct reported names
Typical salary range$130,000–$178,300Middle 50% of yearly wages

Filing & salary trends

How reported activity and wages changed over time

All loaded years · FY 2016–2026
05101520FY 2016: 6 filings16FY 2018: 6 filings18FY 2019: 4 filings19FY 2020: 3 filings20FY 2021: 2 filings21FY 2022: 4 filings22FY 2023: 12 filings23FY 2024: 14 filings24FY 2025: 9 filings25FY 2026: 18 filings · through June26*Fiscal year
FY 2026*18 filings$165,000 median · n=17

*FY 2026 covers Q1–Q3 through June; earlier years cover full fiscal years. Median: certified, positive yearly base wages; nominal USD.

Salary distribution

Where reported yearly base wages concentrate

All loaded years · FY 2016–2026
$125k–$150kMost common wage band
$0$125k$250k+

$25k bands · 71 certified filings with positive yearly wages. Final band includes all wages ≥$250k.

Most reported roles

Explore job mix and compare reported wages

All loaded years · FY 2016–2026
Senior Principal Scientist53
$143,562 median · n=48 eligible
Senior Principal Scientist, Computational Chemistry3
$179,050 median · n=2 eligible
Corporate Senior Principal Scientist Biocompatibility2
$175,000 median · n=1 eligible
Senior Principal Scientist, Nucleic Acid Biology2
$180,000 median · n=2 eligible
Efs-Dd, Senior Principal Scientist1
$161,100 median · n=1 eligible
Senior Principal Scientist - Ts/Ms1
$135,000 median · n=1 eligible
Senior Principal Scientist 20516.588.181
$204,994 median · n=1 eligible
Senior Principal Scientist Bioinformatics1
$154,669 median · n=1 eligible

Top 8 by filing volume. Medians use certified, positive yearly wages. Bars start at zero.

Leading worksite cities

Where filings are concentrated

All loaded years · FY 2016–2026
Cambridge, MA12
$146,197 median · n=12 eligible
South San Francisco, CA8
$172,600 median · n=8 eligible
New York, NY5
$185,800 median · n=3 eligible
Bridgewater, NJ4
$130,000 median · n=3 eligible
Decatur, IL3
$160,000 median · n=3 eligible
Groton, CT3
$146,050 median · n=2 eligible
Morrisville, NC3
$145,142 median · n=3 eligible
Fairfax, VA2
$155,350 median · n=2 eligible

Top 8 by filing volume. Medians use certified, positive yearly wages. Bars start at zero.

Case outcomes

Certification and withdrawal context

All loaded years · FY 2016–2026
91.0%Certified LCAs
Certified71 91.0%
Certified - Withdrawn4 5.1%
Withdrawn3 3.8%

Denominator: all 78 matching filings. LCA certification is not a visa approval rate.

Leading employers

Companies with the most matching filings

All loaded years · FY 2016–2026
Pfizer Inc10
$119,566 median · n=8 eligible
Bristol-Myers Squibb Company5
$170,064 median · n=5 eligible
Novartis Institutes For Biomedical Research, Inc.5
$138,403 median · n=5 eligible
Eli Lilly And Company4
$140,000 median · n=4 eligible
Genentech, Inc.4
$172,600 median · n=4 eligible
Hazen And Sawyer, D.P.C.4
$131,236 median · n=4 eligible
Regeneron Pharmaceuticals, Inc.4
$184,750 median · n=4 eligible
Schrodinger, Inc.4
$196,600 median · n=2 eligible

Top 8 by filing volume. Medians use certified, positive yearly wages. Bars start at zero.

Salary benchmarks

Reported wage percentiles, from P10 to P90

All loaded years · FY 2016–2026
$150,700Median reported annual base wage
10th percentile$111,300
25th percentile$130,000
Median (50th)$150,700
75th percentile$178,300
90th percentile$200,271

n=71 certified filings with positive yearly wages. Percentiles describe filings, not unique workers or total compensation.

Source: U.S. Department of Labor LCA disclosures · FY 2016–2026 (FY 2026 partial) · salary charts exclude non-yearly pay, non-certified cases, and missing or non-positive wages. Coverage & methodology

Salary filing history

78 matching H-1B filings

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Reported base wages in USD · pay period shown beside each amount · select a salary for case details

EmployerJob titleBase salaryLocationSubmit dateStart date
Inov8.Bio Inc.Senior Principal Scientist

Filing details

$190,000 /yr

I-200-26166-015541
Reported wage: $190,000–$205,000 / year
Annualized: $190,000
Status: Certified
Fiscal year: 2026
Decision: 2026-06-23
Employment end: 2029-08-02
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Woburn, MA06/15/202608/03/2026
Amgen Inc.Senior Principal Scientist

Filing details

$211,113.71 /yr

I-200-26161-001103
Reported wage: $211,113.71 / year
Annualized: $211,114
Status: Certified
Fiscal year: 2026
Decision: 2026-06-17
Employment end: 2029-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

South San Francisco, CA06/10/202610/01/2026
Sanofi Us Services Inc.Senior Principal Scientist I, Lab Head, Proteomics

Filing details

$148,500 /yr

I-200-26159-992563
Reported wage: $148,500–$247,500 / year
Annualized: $148,500
Status: Certified
Fiscal year: 2026
Decision: 2026-06-15
Employment end: 2029-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Cambridge, MA06/08/202610/01/2026
Hazen And Sawyer, D.P.C.Senior Principal Scientist

Filing details

$165,000 /yr

I-200-26148-957435
Reported wage: $165,000 / year
Annualized: $165,000
Status: Certified
Fiscal year: 2026
Decision: 2026-06-04
Employment end: 2029-09-29
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Fairfax, VA05/28/202609/30/2026
Hazen And Sawyer, D.P.C.Senior Principal Scientist

Filing details

$145,700 /yr

I-200-26120-852757
Reported wage: $145,700–$145,700.01 / year
Annualized: $145,700
Status: Certified
Fiscal year: 2026
Decision: 2026-05-07
Employment end: 2029-09-29
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Fairfax, VA04/30/202609/30/2026
Genentech, Inc.Senior Principal Scientist

Filing details

$176,600 /yr

I-200-26111-814365
Reported wage: $176,600–$328,000 / year
Annualized: $176,600
Status: Certified
Fiscal year: 2026
Decision: 2026-04-27
Employment end: 2029-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

South San Francisco, CA04/20/202610/01/2026
Janssen Research & Development, LLCSenior Principal Scientist Clin Pharm

Filing details

$201,000 /yr

I-200-26107-806375
Reported wage: $201,000 / year
Annualized: $201,000
Status: Certified
Fiscal year: 2026
Decision: 2026-04-24
Employment end: 2029-08-23
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Titusville, NJ04/17/202608/24/2026
Novartis Institutes For Biomedical Research, Inc.Senior Principal Scientist

Filing details

$143,894 /yr

I-200-26105-796979
Reported wage: $143,894 / year
Annualized: $143,894
Status: Certified
Fiscal year: 2026
Decision: 2026-04-22
Employment end: 2029-04-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Cambridge, MA04/15/202605/01/2026
Archer Daniels Midland CompanySenior Principal Scientist

Filing details

$160,000 /yr

I-200-26103-787600
Reported wage: $160,000–$190,000 / year
Annualized: $160,000
Status: Certified
Fiscal year: 2026
Decision: 2026-04-20
Employment end: 2029-09-14
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Decatur, IL04/13/202609/15/2026
Amgen Inc.Senior Principal Scientist

Filing details

$211,113.71 /yr

I-200-26096-760721
Reported wage: $211,113.71 / year
Annualized: $211,114
Status: Certified
Fiscal year: 2026
Decision: 2026-04-13
Employment end: 2029-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

South San Francisco, CA04/06/202610/01/2026
Tcg Greenchem, IncSenior Principal Scientist

Filing details

$126,080 /yr

I-200-26093-755618
Reported wage: $126,080 / year
Annualized: $126,080
Status: Certified
Fiscal year: 2026
Decision: 2026-04-10
Employment end: 2029-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Ewing, NJ04/03/202610/01/2026
Schrodinger, Inc.Senior Principal Scientist, Computational Chemistry

Filing details

$207,400 /yr

I-200-26077-713403
Reported wage: $207,400 / year
Annualized: $207,400
Status: Certified
Fiscal year: 2026
Decision: 2026-03-25
Employment end: 2029-08-21
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

New York, NY03/18/202608/22/2026
Schrodinger, Inc.Senior Principal Scientist, Computational Chemistry

Filing details

$207,400 /yr

I-200-26071-699463
Reported wage: $207,400 / year
Annualized: $207,400
Status: Withdrawn
Fiscal year: 2026
Decision: 2026-03-18
Employment end: 2029-08-21
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

New York, NY03/12/202608/22/2026
Epic Pharma LLCSenior Principal Scientist

Filing details

$145,000 /yr

I-200-26040-628455
Reported wage: $145,000 / year
Annualized: $145,000
Status: Certified
Fiscal year: 2026
Decision: 2026-02-17
Employment end: 2029-02-15
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Laurelton, NY02/09/202602/16/2026
Regeneron Pharmaceuticals, Inc.Senior Principal Scientist-Process Development

Filing details

$200,270.62 /yr

I-200-26021-574226
Reported wage: $200,270.62 / year
Annualized: $200,271
Status: Certified
Fiscal year: 2026
Decision: 2026-01-27
Employment end: 2029-07-18
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Cambridge, MA01/20/202607/19/2026
Regeneron Pharmaceuticals, Inc.Senior Principal Scientist

Filing details

$186,102.71 /yr

I-200-26012-553112
Reported wage: $186,102.71 / year
Annualized: $186,103
Status: Certified
Fiscal year: 2026
Decision: 2026-01-20
Employment end: 2029-07-10
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Tarrytown, NY01/12/202607/11/2026
Pfizer Inc.Efs-Dd, Senior Principal Scientist

Filing details

$161,100 /yr

I-200-25350-487761
Reported wage: $161,100 / year
Annualized: $161,100
Status: Certified
Fiscal year: 2026
Decision: 2025-12-23
Employment end: 2029-01-04
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Cambridge, MA12/16/202501/05/2026
Tate & Lyle Solutions USA, LLCSenior Principal Scientist, Ingredient Science

Filing details

$155,000 /yr

I-200-25322-419120
Reported wage: $155,000 / year
Annualized: $155,000
Status: Certified
Fiscal year: 2026
Decision: 2025-11-25
Employment end: 2028-12-14
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Hoffman Estates, IL11/18/202512/15/2025
The Jackson LaboratorySenior Principal Scientist, Functional Genomics

Filing details

$152,000 /yr

I-200-25231-251560
Reported wage: $152,000–$252,101 / year
Annualized: $152,000
Status: Certified
Fiscal year: 2025
Decision: 2025-08-26
Employment end: 2028-09-14
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

New York, NY08/19/202509/15/2025
Janssen Research & Development, LLCSenior Principal Scientist Pharmacometrics

Filing details

$192,240 /yr

I-200-25188-155731
Reported wage: $192,240 / year
Annualized: $192,240
Status: Certified
Fiscal year: 2025
Decision: 2025-07-14
Employment end: 2028-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Spring House, PA07/07/202510/01/2025
Bristol-Myers Squibb CompanySenior Principal Scientist

Filing details

$170,063.91 /yr

I-200-25142-008235
Reported wage: $170,063.91 / year
Annualized: $170,064
Status: Certified
Fiscal year: 2025
Decision: 2025-05-30
Employment end: 2028-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Seattle, WA05/22/202510/01/2025
Leal Therapeutics, Inc.Senior Principal Scientist, Nucleic Acid Biology

Filing details

$180,000 /yr

I-200-25073-778431
Reported wage: $180,000 / year
Annualized: $180,000
Status: Certified
Fiscal year: 2025
Decision: 2025-03-21
Employment end: 2028-03-16
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Newton, MA03/14/202503/17/2025
Conmed CorporationCorporate Senior Principal Scientist Biocompatibility

Filing details

$175,000 /yr

I-200-25070-766290
Reported wage: $175,000 / year
Annualized: $175,000
Status: Certified
Fiscal year: 2025
Decision: 2025-03-18
Employment end: 2028-03-23
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Largo, FL03/11/202503/24/2025
Pfizer Inc.Senior Principal Scientist

Filing details

$120,800 /yr

I-200-25066-757194
Reported wage: $120,800–$241,700 / year
Annualized: $120,800
Status: Certified
Fiscal year: 2025
Decision: 2025-03-14
Employment end: 2028-08-10
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Bothell, WA03/07/202508/11/2025
Leal Therapeutics, Inc.Senior Principal Scientist, Nucleic Acid Biology

Filing details

$180,000 /yr

I-200-25065-750487
Reported wage: $180,000 / year
Annualized: $180,000
Status: Certified
Fiscal year: 2025
Decision: 2025-03-13
Employment end: 2028-05-22
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Newton, MA03/06/202505/23/2025

These records describe employer-reported wages, not total compensation. A certified LCA does not establish that a visa was granted or that an employer is currently hiring. Read the methodology and coverage.