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Manager, Regulatory Operations

Reported H-1B wages for this job title. Explore roles, wages, and case statuses using public Department of Labor records.

Insights follow the displayed search filters, including partial name matches. All loaded years.

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THE BIG PICTURE

Manager, Regulatory Operations insights

Official U.S. DOL records
Total filings37All loaded years · FY 2016–2026
Median yearly base salary$130,00032 eligible salary records
Employer names23Distinct reported names
Typical salary range$111,925–$139,949Middle 50% of yearly wages

Filing & salary trends

How reported activity and wages changed over time

All loaded years · FY 2016–2026
02468FY 2018: 3 filings18FY 2019: 2 filings19FY 2020: 3 filings20FY 2021: 4 filings21FY 2022: 7 filings22FY 2023: 5 filings23FY 2024: 5 filings24FY 2025: 5 filings25FY 2026: 3 filings · through June26*Fiscal year
FY 2026*3 filings$188,500 median · n=3

*FY 2026 covers Q1–Q3 through June; earlier years cover full fiscal years. Median: certified, positive yearly base wages; nominal USD.

Salary distribution

Where reported yearly base wages concentrate

All loaded years · FY 2016–2026
$125k–$150kMost common wage band
$0$125k$250k+

$25k bands · 32 certified filings with positive yearly wages. Final band includes all wages ≥$250k.

Most reported roles

Explore job mix and compare reported wages

All loaded years · FY 2016–2026
Manager, Regulatory Operations22
$120,000 median · n=18 eligible
Senior Manager, Regulatory Operations5
$170,000 median · n=5 eligible
Associate Manager, Regulatory Operations3
$118,450 median · n=3 eligible
Manager, Regulatory Operations, Labeling And Compliance2
$130,000 median · n=1 eligible
Business Integration Manager, Regulatory Operations1
$140,000 median · n=1 eligible
Manager, Regulatory Operations, Clinical Research & Regulato1
$90,000 median · n=1 eligible
Manager, Regulatory Operations Publishing1
$130,000 median · n=1 eligible
Senior Manager, Regulatory Operations And Publishing1
$187,000 median · n=1 eligible

Top 8 by filing volume. Medians use certified, positive yearly wages. Bars start at zero.

Leading worksite cities

Where filings are concentrated

All loaded years · FY 2016–2026
Cambridge, MA5
$120,500 median · n=2 eligible
Newton, MA4
$179,250 median · n=4 eligible
Somerset, NJ4
$115,963 median · n=4 eligible
New York, NY3
$105,000 median · n=3 eligible
Princeton, NJ3
$120,000 median · n=3 eligible
San Rafael, CA2
$131,269 median · n=1 eligible
Basking Ridge, NJ1
$125,000 median · n=1 eligible
Cambridge, MASSACHUSETTS1
$133,000 median · n=1 eligible

Top 8 by filing volume. Medians use certified, positive yearly wages. Bars start at zero.

Case outcomes

Certification and withdrawal context

All loaded years · FY 2016–2026
86.5%Certified LCAs
Certified32 86.5%
Certified - Withdrawn4 10.8%
Withdrawn1 2.7%

Denominator: all 37 matching filings. LCA certification is not a visa approval rate.

Leading employers

Companies with the most matching filings

All loaded years · FY 2016–2026
Karyopharm Therapeutics Inc.6
$165,343 median · n=6 eligible
Legend Biotech Usa Inc.4
$115,963 median · n=4 eligible
Agios Pharmaceuticals, Inc.3
$118,450 median · n=3 eligible
Otsuka Pharmaceutical Development & Commercialization, Inc.3
$120,000 median · n=3 eligible
Sage Therapeutics, Inc.3
$135,000 median · n=3 eligible
Biomarin Pharmaceutical Inc.2
$131,269 median · n=1 eligible
Kadmon Corporation, LLC2
— median · n=0 eligible
Prevail Therapeutics, Inc.2
$105,000 median · n=2 eligible

Top 8 by filing volume. Medians use certified, positive yearly wages. Bars start at zero.

Salary benchmarks

Reported wage percentiles, from P10 to P90

All loaded years · FY 2016–2026
$130,000Median reported annual base wage
10th percentile$109,034
25th percentile$111,925
Median (50th)$130,000
75th percentile$139,949
90th percentile$169,750

n=32 certified filings with positive yearly wages. Percentiles describe filings, not unique workers or total compensation.

Source: U.S. Department of Labor LCA disclosures · FY 2016–2026 (FY 2026 partial) · salary charts exclude non-yearly pay, non-certified cases, and missing or non-positive wages. Coverage & methodology

Salary filing history

37 matching H-1B filings

Export page CSV

Reported base wages in USD · pay period shown beside each amount · select a salary for case details

EmployerJob titleBase salaryLocationSubmit dateStart date
Karyopharm Therapeutics Inc.Senior Manager, Regulatory Operations

Filing details

$190,215 /yr

I-200-26079-718687
Reported wage: $190,215 / year
Annualized: $190,215
Status: Certified
Fiscal year: 2026
Decision: 2026-03-27
Employment end: 2029-08-31
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Newton, MA03/20/202609/01/2026
Karyopharm Therapeutics Inc.Senior Manager, Regulatory Operations

Filing details

$188,500.08 /yr

I-200-26079-719694
Reported wage: $188,500.08 / year
Annualized: $188,500
Status: Certified
Fiscal year: 2026
Decision: 2026-03-27
Employment end: 2029-08-31
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Newton, MA03/20/202609/01/2026
Agios Pharmaceuticals, Inc.Manager, Regulatory Operations

Filing details

$139,050 /yr

I-200-25345-474782
Reported wage: $139,050 / year
Annualized: $139,050
Status: Certified
Fiscal year: 2026
Decision: 2025-12-18
Employment end: 2029-06-10
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Spartanburg, SC12/11/202506/11/2026
Karyopharm Therapeutics Inc.Manager, Regulatory Operations

Filing details

$139,932 /yr

I-200-25190-161262
Reported wage: $139,932 / year
Annualized: $139,932
Status: Certified
Fiscal year: 2025
Decision: 2025-07-16
Employment end: 2027-06-18
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Morrisville, NC07/09/202507/14/2025
Legend Biotech USA, Inc.Sr. Manager, Regulatory Operations

Filing details

$145,710.24 /yr

I-200-25188-156107
Reported wage: $145,710.24 / year
Annualized: $145,710
Status: Certified
Fiscal year: 2025
Decision: 2025-07-14
Employment end: 2028-12-31
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Somerset, NJ07/07/202501/01/2026
Vera TherapeuticsSenior Manager, Regulatory Operations And Publishing

Filing details

$187,000 /yr

I-200-25037-669885
Reported wage: $187,000–$238,000 / year
Annualized: $187,000
Status: Certified
Fiscal year: 2025
Decision: 2025-02-12
Employment end: 2028-03-16
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Lathrop, CA02/05/202503/17/2025
Takeda Vaccines Inc.Manager, Regulatory Operations, Labeling And Compliance

Filing details

$137,783.1 /yr

I-200-23201-203472
Reported wage: $137,783.1 / year
Annualized: $137,783
Status: Certified - Withdrawn
Fiscal year: 2025
Decision: 2024-12-04
Employment end: 2026-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Northlake, TX07/20/202310/01/2023
Legend Biotech USA Inc.Manager, Regulatory Operations

Filing details

$111,925 /yr

I-200-24319-475031
Reported wage: $111,925 / year
Annualized: $111,925
Status: Certified
Fiscal year: 2025
Decision: 2024-11-21
Employment end: 2027-12-31
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Somerset, NJ11/14/202401/01/2025
Otsuka Pharmaceutical Development & Commercialization, Inc.Manager, Regulatory Operations

Filing details

$109,034 /yr

I-200-24262-348062
Reported wage: $109,034–$145,640 / year
Annualized: $109,034
Status: Certified
Fiscal year: 2024
Decision: 2024-09-25
Employment end: 2028-03-02
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Princeton, NJ09/18/202403/03/2025
Legend Biotech USA Inc.Manager, Regulatory Operations

Filing details

$111,925 /yr

I-200-24213-234152
Reported wage: $111,925 / year
Annualized: $111,925
Status: Certified
Fiscal year: 2024
Decision: 2024-08-07
Employment end: 2027-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Somerset, NJ07/31/202410/01/2024
Cytokinetics, Inc.Manager, Regulatory Operations

Filing details

$116,250 /yr

I-200-24022-658145
Reported wage: $116,250–$193,750 / year
Annualized: $116,250
Status: Certified
Fiscal year: 2024
Decision: 2024-01-29
Employment end: 2027-07-05
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

South San Francisco, CA01/22/202407/06/2024
Kadmon Corporation, LLCManager, Regulatory Operations

Filing details

$120,000 /yr

I-200-21139-326904
Reported wage: $120,000 / year
Annualized: $120,000
Status: Certified - Withdrawn
Fiscal year: 2024
Decision: 2024-01-09
Employment end: 2024-06-13
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Cambridge, MA05/19/202106/14/2021
Otsuka Pharmaceutical Development & Commercialization, Inc.Manager, Regulatory Operations

Filing details

$125,000 /yr

I-200-23269-383257
Reported wage: $125,000–$135,000 / year
Annualized: $125,000
Status: Certified
Fiscal year: 2024
Decision: 2023-10-03
Employment end: 2027-02-28
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Princeton, NJ09/26/202302/29/2024
Agios Pharmaceuticals, Inc.Associate Manager, Regulatory Operations

Filing details

$118,450.08 /yr

I-200-23159-091540
Reported wage: $118,450.08 / year
Annualized: $118,450
Status: Certified
Fiscal year: 2023
Decision: 2023-06-15
Employment end: 2026-06-11
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Roebuck, SC06/08/202306/12/2023
Karyopharm Therapeutics Inc.Manager, Regulatory Operations

Filing details

$130,000 /yr

I-200-23104-934396
Reported wage: $130,000 / year
Annualized: $130,000
Status: Certified
Fiscal year: 2023
Decision: 2023-04-21
Employment end: 2026-08-31
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Des Plaines, IL04/14/202309/01/2023
Karyopharm Therapeutics Inc.Senior Manager, Regulatory Operations

Filing details

$170,000 /yr

I-200-23089-889620
Reported wage: $170,000 / year
Annualized: $170,000
Status: Certified
Fiscal year: 2023
Decision: 2023-04-06
Employment end: 2026-08-31
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Newton, MA03/30/202309/01/2023
Karyopharm Therapeutics Inc.Senior Manager, Regulatory Operations

Filing details

$160,685 /yr

I-200-23089-889988
Reported wage: $160,685 / year
Annualized: $160,685
Status: Certified
Fiscal year: 2023
Decision: 2023-04-06
Employment end: 2026-08-31
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Newton, MA03/30/202309/01/2023
Sage Therapeutics, Inc.Manager, Regulatory Operations

Filing details

$135,000 /yr

I-200-23068-834152
Reported wage: $135,000 / year
Annualized: $135,000
Status: Certified
Fiscal year: 2023
Decision: 2023-03-15
Employment end: 2025-04-05
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Dallas, TX03/08/202303/17/2023
Otsuka Pharmaceutical Development & Commercialization, Inc.Manager, Regulatory Operations

Filing details

$120,000 /yr

I-200-22174-307167
Reported wage: $120,000–$130,000 / year
Annualized: $120,000
Status: Certified
Fiscal year: 2022
Decision: 2022-06-30
Employment end: 2025-12-15
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Princeton, NJ06/23/202212/16/2022
Revolution Medicines, Inc.Senior Manager, Regulatory Operations

Filing details

$167,500 /yr

I-200-22129-152575
Reported wage: $167,500 / year
Annualized: $167,500
Status: Certified
Fiscal year: 2022
Decision: 2022-05-16
Employment end: 2025-05-31
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Seattle, WA05/09/202206/01/2022
Sage Therapeutics, Inc.Manager, Regulatory Operations

Filing details

$135,000 /yr

I-200-22088-018734
Reported wage: $135,000 / year
Annualized: $135,000
Status: Certified
Fiscal year: 2022
Decision: 2022-04-05
Employment end: 2025-04-05
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Netcong, NJ03/29/202204/06/2022
Sierra Oncology, Inc.Manager, Regulatory Operations Publishing

Filing details

$130,000 /yr

I-200-22034-875374
Reported wage: $130,000 / year
Annualized: $130,000
Status: Certified
Fiscal year: 2022
Decision: 2022-02-10
Employment end: 2025-02-04
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Dublin, CA02/03/202202/05/2022
Legend Biotech USA IncManager, Regulatory Operations

Filing details

$120,000 /yr

I-200-21364-792594
Reported wage: $120,000 / year
Annualized: $120,000
Status: Certified
Fiscal year: 2022
Decision: 2022-01-06
Employment end: 2024-09-30
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

Somerset, NJ12/29/202102/28/2022
Eli Lilly And CompanyManager, Regulatory Operations

Filing details

$109,034 /yr

I-200-21327-722741
Reported wage: $109,034–$172,500 / year
Annualized: $109,034
Status: Certified
Fiscal year: 2022
Decision: 2021-12-01
Employment end: 2025-01-02
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

New York, NY11/23/202101/03/2022
Biomarin Pharmaceutical Inc.Manager, Regulatory Operations

Filing details

$142,084 /yr

I-200-20309-898344
Reported wage: $142,084–$161,400 / year
Annualized: $142,084
Status: Certified - Withdrawn
Fiscal year: 2022
Decision: 2021-10-07
Employment end: 2024-04-29
Worker positions: 1

Employer-reported disclosure · Base wage, not total compensation.

San Rafael, CA11/04/202004/30/2021

These records describe employer-reported wages, not total compensation. A certified LCA does not establish that a visa was granted or that an employer is currently hiring. Read the methodology and coverage.